NSAIDs are a very common type of anti-inflammatory medication. Some forms of NSAIDs are available over the counter, such as ibuprofen, while other forms of NSAIDs require a prescription. NSAIDs are often a first-line treatment (what someone tries first) to help treat pain and inflammation from rheumatoid arthritis.
NSAIDs work by helping the body to block the production of a hormone-like chemical called prostaglandin. The body naturally produces prostaglandins to help regulate many systems in the body, including responding to acute injuries or pain. Prostaglandins contribute to inflammation and redness at the site of injury. However, for a more chronic condition like arthritis, too much prostaglandin production can lead to chronic inflammation and pain around the affected joints. NSAIDs help by temporarily blocking the body’s ability to produce prostaglandins and help reduce the amount of inflammation and pain. It is always best to speak with your doctor or pharmacist about how and when to take NSAIDs. Taking NSAIDs at the first sign of a flare, before the body can produce excess prostaglandins, may be more effective than starting it in the middle of a flare.
While NSAIDs can ease the symptoms of rheumatoid arthritis, it is important to note they are a temporary option that help with symptoms but once stopped, symptoms may return. NSAIDs do not control the underlying problem, which is an overactive immune system, which is why your rheumatologist will recommend a rheumatoid arthritis specific treatment.