Leflunomide (LEF)

Drug Name
Leflunomide (LEF)

Brand Name(s)
Arava®, generics

Drug Class
Disease-Modifying Anti-Rheumatic Drug (DMARD)

Leflunomide (LEF) is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid and psoriatic arthritis.


This information was last updated November 2017, with expert advice from:

Jason Kielly, B.Sc. (pharm.), Pharm.D.
Assistant Professor, School of Pharmacy, Memorial University of Newfoundland
Clinical Pharmacist, Rheumatic Health Program, Eastern Health

This information was last updated in December 2021 by:

Alan Low, B.Sc. (pharm.), Pharm. D., ACPR, FCSHP, CCD, RPh
Clinical Associate Professor, Faculty of Pharmaceutical Sciences, UBC
Co-Founder and Executive Director, Medicines Access Coalition – BC
​Primary Care Pharmacist, Vancouver

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