Like all medications, taking LEF carries some risk of side effects, which must be balanced with the potential benefits. Overall, the risk of joint damage and permanent disability (resulting from arthritis) is much greater than the risks of side effects from LEF. When monitored properly the vast majority of side effects are rare, generally improve over time and are reversible.
The most common side effects of LEF is nausea. This usually gets better over time as you get used to taking the medication. LEF can also cause diarrhea, which can be severe. If you develop diarrhea contact your health-care provider. Some people may notice a decreased appetite and weight loss while taking LEF. Let your health-care provider know if you are losing weight while taking LEF.
In some rare cases, people experience a skin rash, thinning of the hair and the feeling of “pins and needles” or tingling in the hands and feet. Talk to your health-care provider if you experience any of these effects.
Also, in rare occurrences, LEF can cause an increase in blood pressure. If you already have high blood pressure, please discuss this with your health-care provider before starting LEF.
LEF may affect your liver and blood counts. This should be closely monitored with routine blood work.
Lastly, LEF may cause lung problems in rare circumstances. Please contact your health-care provider if you develop new shortness of breath or a new, prolonged cough while taking LEF.