Like all medications, taking golimumab carries some risk of side effects, which must be balanced with the potential benefits. In general, the risk of joint damage and permanent disability (resulting from arthritis) is much greater than the risks of side effects from golimumab. When monitored properly the vast majority of side effects are rare, most improve over time and are reversible.
Firstly, golimumab can increase your risk of infections.
In rare cases, golimumab can cause an allergic reaction during the infusion (flushing, itching, changes in heart rate and blood pressure, etc.). A health-care professional will monitor for this reaction during the infusion.
For people taking the medication by injection, golimumab can in rare circumstances cause a reaction (redness, pain and itching) at the injection site. Talk to your health-care provider if these symptoms become severe.
In uncommon cases, some people experience headaches while taking golimumab. If this becomes severe please consult your health-care provider.
Some people have developed lupus-like symptoms that disappeared after the medication was ceased. If you have chest pains that do not go away, shortness of breath or a rash on your cheeks or arms that gets worse in the sun, call your doctor right away.
There have been rare cases of disorders that affect the nervous system of people taking golimumab or other TNF-blockers. Signs that you could be experiencing a problem affecting your nervous system include: numbness or tingling, problems with your vision, weakness in your legs and dizziness.
Golimumab very rarely can cause a drop in blood counts.