Nausea, constipation, dry mouth, fatigue, dizziness, drowsiness, headache (rarely), increased blood pressure/heart rate, sweating and decreased appetite. If any of these symptoms become bothersome, please speak to your healthcare provider.
Suicidal thoughts or behavior, and self-injury have been very rarely reported in patients taking SNRI medications, like duloxetine. Discuss these risks with your healthcare provider prior to starting duloxetine. Contact your healthcare provider if you experience worsening depression or thoughts of suicide while taking duloxetine.
Do not discontinue or reduce your dosage of duloxetine without speaking with your healthcare provider. Duloxetine should be discontinued slowly, typically over a week or two.