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Two knee replacements by my mid-40s

Sharmila Sriram was just 29 years old when her knee gave out during a kickboxing class. In the weeks that followed, the inflammation in her knee spread to her ankle and then to her wrist. It would take a year before Sriram would finally have a diagnosis: seronegative rheumatoid arthritis.

The condition involves the body’s immune system attacking the lining of the joints, which can cause pain, stiffness, swelling, and can eventually lead to long-term joint damage . Patients with seronegative rheumatoid arthritis typically have lower levels of rheumatoid factor in the blood, making it more difficult to diagnose. It is believed that one per cent of the Canadian population has rheumatoid arthritis.

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