Drug Name

Brand Name(s)
Short Acting: Tramacet® and generics (tramadol 37.5 mg and acetaminophen 325 mg), Ultram® (tramadol 50 mg) Long Acting: Durela®, Ralivia®, Tridural® and Zytram XL®

Drug Class
Prescription medication

Tramadol is as an alternative treatment option for osteoarthritis (OA) of the knee and hip for people who have failed treatment with acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) or cannot take these medications.

This information was written in November 2017, with expert advice from:

Jason Kielly, B.Sc. (pharm.), Pharm.D.
Assistant Professor, School of Pharmacy, Memorial University of Newfoundland
Clinical Pharmacist, Rheumatic Health Program, Eastern Health

This information was last updated in December 2021 by:

Alan Low, B.Sc. (pharm.), Pharm. D., ACPR, FCSHP, CCD, RPh
Clinical Associate Professor, Faculty of Pharmaceutical Sciences, UBC
Co-Founder and Executive Director, Medicines Access Coalition – BC
Primary Care Pharmacist, Vancouver

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