Secukinumab can make it more difficult for your body to fight infections. People with active infections should not take secukinumab. If you have a fever, think you have an infection or have been prescribed an antibiotic, contact your health-care provider. People who have had frequent infections in the past or a history of tuberculosis should discuss the use of secukinumab with their prescriber.
Also contact your health-care provider if you are having surgery as you may need to stop secukinumab until you are healed and there is no sign of infection.
Secukinumab has not been studied in pregnant women or nursing mothers so its effect(s) on pregnant women or nursing babies are unknown. You should tell your doctor if you are pregnant or are planning to become pregnant. Because of the potential for adverse reactions in nursing infants, a decision should be made on whether or not to discontinue nursing or the medication, taking into account the importance of the drug to the mother.
Anyone who has had a previous allergic reaction to secukinumab should avoid the medication. The removable cap of the prefilled syringes and pens contains a derivative of latex. Caution is advised if you have a latex allergy.
Before starting secukinumab tell your health-care provider if you have inflammatory bowel disease (Crohn’s or ulcerative colitis). Secukinumab can cause new onset or flares of inflammatory bowel disease. Tell your health-care provider if you develop diarrhea while taking secukinumab.
Ideally, your vaccinations should be up to date prior to starting secukinumab. If you have already started therapy with secukinumab, your health-care provider will likely recommend most inactive vaccines (e.g., influenza, pneumococcal). Live vaccines are not recommended due to risk of causing infection. Before receiving any vaccinations while taking secukinumab, you should speak with your health-care provider.