Like all medications, taking ixekizumab carries some risk of side effects, which must be balanced with the potential benefits. In general, the risk of joint damage and permanent disability (resulting from arthritis) is much greater than the risks of side effects from ixekizumab. When monitored properly the vast majority of side effects are rare, most improve over time and are reversible.
Firstly, as with all DMARD and biologic medications, ixekizumab can lower the ability of your immune system to fight infections and increase your risk of infections.
The most commonly reported side effect with ixekizumab is symptoms of a cold (sore throat, stuffy nose). Ixekizumab can cause a reaction (redness, pain, and itching) at the injection site. Other commonly reported symptoms include nausea and athlete’s foot. Talk to your health-care provider if any of these symptoms affect you severely.
Rarely ixekizumab can cause a serious allergic reaction (feeling faint, swelling of the face, eyelids, tongue, lips, mouth or throat, trouble breathing, chest tightness). If you have troublesome symptoms talk to your health-care provider.