Celecoxib is used for both inflammatory arthritis, such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS), and is a first-line treatment for osteoarthritis (OA). Celecoxib is an NSAID that blocks an enzyme called cyclooxygenase-2 (COX-2) which plays a role in inflammation. By blocking COX-2, celecoxib reduces pain and inflammation in the body. Celecoxib may cause stomach upset which can be relieved by taking it with food.
This information was last updated in June 2024 with expert review and advice by:
Alan Low, BSc(Pharm), PharmD, ACPR, FCSHP, CCD, RPh
Clinical Professor, Faculty of Pharmaceutical Sciences, University of British Columbia
Pharmacy Lead and Primary Care Pharmacist, BioPro Biologics Pharmacy
Care Director, MedInfuse Health
Garrett Tang, PharmD, RPh
Pharmacist Services Coordinator, MedInfuse Health
We also thank previous expert contributor:
Jason Kielly, BSc(Pharm), PharmD
Assistant Professor, School of Pharmacy, Memorial University of Newfoundland
Clinical Pharmacist, Rheumatic Health Program, Eastern Health
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