Taking anakinra can make it more difficult for your body to fight infection. Therefore, people with active infections should not take anakinra. If you have a fever, think you have an infection or have been prescribed an antibiotic, contact your healthcare provider. People who have had frequent infections in the past or a history of tuberculosis should discuss the use of anakinra with their healthcare provider.
Also contact your healthcare provider if you are having surgery as you may need to stop anakinra until you are healed and there is no sign of infection.
Anakinra has not been studied in pregnant people or lactating parents so its effect(s) on pregnant people or nursing babies are unknown. Anakinra should not be administered to pregnant people unless the benefits outweigh the potential risks. You should tell your doctor if you are pregnant or are planning to become pregnant. Because of the potential for adverse reactions in nursing infants, a decision should be made with your healthcare provider on whether or not to discontinue nursing or the medication, taking into account the importance of the drug to the lactating parent.
Anyone who has had a previous allergic reaction to anakinra should avoid the medication.
People with a history of cancer or emphysema should discuss the use of anakinra with their healthcare provider.
Make sure that your vaccinations are up to date before starting anakinra. Your healthcare provider will likely recommend a number of vaccines (e.g., influenzae, pneumonia, RSV, shingles) to get beforehand. Because anakinra can reduce your ability to react to vaccines, you should wait at least two to three weeks after your vaccine before starting anakinra. If you are already on anakinra and need a vaccination, try to space it as long as you can after your last dose. Live vaccines are not recommended due to risk of causing infection. Before receiving any vaccinations while taking anakinra, you should speak with your healthcare provider.