Upadacitinib is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondyloarthritis (AS), by inhibiting an enzyme called Janus kinase which would otherwise trigger numerous inflammatory reactions. It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Type of Arthritis: Rheumatoid Arthritis
Tofacitinib
Tofacitinib is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA), by inhibiting an enzyme called Janus kinase (JAK) which would otherwise trigger numerous inflammatory reactions. It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Tocilizumab
Tocilizumab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA). It works by blocking interleukin-6 (IL-6), a protein which is involved in the body’s inflammatory response. Tocilizumab can help suppress an overactive immune system, but can also increase your risk for certain infections.
Sulfasalazine (SSZ)
SSZ is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA). It is also used for treatment of inflammatory bowel disease and other immune disorders.
Sarilumab
Sarilumab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), by binding to IL-6 and preventing it from causing inflammation. It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Rituximab
Rituximab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and granulomatosis with polyangiitis (GPA, also known as Wegener’s Granulomatosis). Rituximab works by stopping B-cells from triggering an immune response against the body’s own tissues. It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Prednisone
Prednisone is a steroid used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA), ankylosing spondylitis(AS), juvenile idiopathic arthritis (JIA), acute gouty arthritis, lupus, and polymyalgia rheumatica. It is a potent and fast-acting anti-inflammatory agent, but can cause stomach upset and long-term use can cause diabetes, weight gain, high blood pressure, osteoporosis, and mood changes.
Methotrexate (MTX)
MTX is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA) by slowing cell replication which can stop your immune cells from replicating out of control. You may feel unwell 24-48 hours after taking methotrexate. This feeling should go away after a few weeks of therapy and your doctor may recommend folic. . .
Leflunomide (LEF)
Leflunomide (LEF) is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Leflunomide is thought to suppress the immune system by blocking T-cell activity. You may experience nausea or diarrhea while on leflunomide. This side effect should be transient but taking leflunomide before bed may help to mitigate the effects.
