Guselkumab is used to treat inflammatory types of arthritis, such as psoriatic arthritis (PsA), by blocking inflammatory protein interleukin-23 (IL-23). It can help suppress an overactive immune system, but can also increase your risk for certain infections.
This information was last updated in April 2025 with expert review and advice by:
Alan Low, BSc(Pharm), PharmD, ACPR, FCSHP, CCD, RPh
Clinical Professor, Faculty of Pharmaceutical Sciences, University of British Columbia
Pharmacy Lead and Primary Care Pharmacist, BioPro Biologics Pharmacy
Care Director, MedInfuse Health
Garrett Tang, PharmD, RPh
Pharmacist Services Coordinator, MedInfuse Health
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