Sarilumab

Sarilumab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), by binding to IL-6 and preventing it from causing inflammation. It can help suppress an overactive immune system, but can also increase your risk for certain infections.

Rituximab

Rituximab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and granulomatosis with polyangiitis (GPA, also known as Wegener’s Granulomatosis). Rituximab works by stopping B-cells from triggering an immune response against the body’s own tissues. It can help suppress an overactive immune system, but can also increase your risk for certain infections.

Proton Pump Inhibitors (PPIs)

PPIs are a class of medications that work by stopping your stomach from producing ulcer-causing acid. When taken with an NSAID, PPIs reduce the risk of developing ulcers and promote ulcer healing. For the best effects, it should be taken 30 minutes before breakfast.

Prednisone

Prednisone is a steroid used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA), ankylosing spondylitis(AS), juvenile idiopathic arthritis (JIA), acute gouty arthritis, lupus, and polymyalgia rheumatica. It is a potent and fast-acting anti-inflammatory agent, but can cause stomach upset and long-term use can cause diabetes, weight gain, high blood pressure, osteoporosis, and mood changes.

Opioids

Opioids are second-line medications reserved for moderate to severe knee and hip osteoarthritis (OA) pain that does not respond to adequate trials of other therapies (acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), tramadol, duloxetine). Opioids trigger your body’s natural pain-relief mechanism. Tolerance to this medication develops rapidly and can lead to dependency or addiction in some people. Courses of opioids should be limited. . .

Non-Steroidal Anti-inflammatory Drugs (NSAIDs)

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) refers to a group of medications which are used for both inflammatory arthritis and osteoarthritis (OA). Some examples of NSAIDs are acetylsalicylic acid (ASA), celecoxib, diclofenac, flurbiprofen, ibuprofen, indomethacin, ketoprofen, ketorolac, meloxicam, nabumetone, naproxen, piroxicam, and sulindac. NSAIDs can help relieve pain associated with many conditions and reduce inflammation. NSAIDs block enzymes that trigger inflammation to. . .

Misoprostol

Misoprostol replaces a naturally occurring substance that helps maintain the stomach’s protective mucous lining. It is one of the ingredients in some combination tablets used for arthritis pain. Misoprostol is used to reduce the risk of stomach ulcers in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs).

Methotrexate (MTX)

MTX is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA) by slowing cell replication which can stop your immune cells from replicating out of control. You may feel unwell 24-48 hours after taking methotrexate. This feeling should go away after a few weeks of therapy and your doctor may recommend folic. . .

Leflunomide (LEF)

Leflunomide (LEF) is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Leflunomide is thought to suppress the immune system by blocking T-cell activity. You may experience nausea or diarrhea while on leflunomide. This side effect should be transient but taking leflunomide before bed may help to mitigate the effects.

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