Leflunomide (LEF) is a DMARD used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Leflunomide is thought to suppress the immune system by blocking T-cell activity. You may experience nausea or diarrhea while on leflunomide. This side effect should be transient but taking leflunomide before bed may help to mitigate the effects.
Drug Class: Disease-Modifying Anti-Rheumatic Drug (DMARD)
Ixekizumab
Ixekizumab is used to treat inflammatory types of arthritis, such as psoriatic arthritis (PsA) and ankylosing spondylitis (AS) by blocking interleukin-17, a molecule that triggers inflammation. It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Infliximab
Infliximab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS). It is also used to treat Crohn’s disease, ulcerative colitis and plaque psoriasis. It can help suppress an overactive immune system, but can also increase your risk for certain infections. There are biosimilar versions of infliximab, which are highly. . .
Hydroxychloroquine (HCQ)
HCQ is a DMARD used as first-line treatment for systemic lupus erythematosus (SLE) and second-line treatment for rheumatoid arthritis (RA). It dampens an overactive immune system by stopping you from making antibodies against your own cells. HCQ is very well tolerated but you will need to get vision and heart rhythm check-ups while on this medication.
Guselkumab
Guselkumab is used to treat inflammatory types of arthritis, such as psoriatic arthritis (PsA), by blocking inflammatory protein interleukin-23 (IL-23). It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Golimumab
Golimumab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS). Golimumab treats arthritis by binding to tumour necrosis factor (TNF) and preventing it from causing inflammation. It can help suppress an overactive immune system, but can also increase your risk for certain infections.
Etanercept
Etanercept is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), juvenile idiopathic arthritis (JIA), and ankylosing spondylitis (AS), by binding to tumour necrosis factor (TNF) and preventing it from causing inflammation. Etanercept can help suppress an overactive immune system but can also increase your risk of certain infections. There are biosimilar versions of etanercept, which. . .
Certolizumab Pegol
Certolizumab is used to treat inflammatory types of arthritis, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) by blocking tumour necrosis factor (TNF) and preventing it from causing inflammation. Certolizumab suppresses the body’s immune system but can also increase your risk of certain infections.
Bimekizumab
Bimekizumab is used to treat inflammatory conditions such as ankylosing spondylitis (AS), non-radiographic axial spondyloarthritis, psoriatic arthritis (PsA), and psoriasis. It works by binding to an inflammatory cytokine called IL-17A and IL-17F to reduce inflammation. Since it affects the immune system, it can also increase the risk of infections.
